Figure 1 Multiple alignment of a conserved region in the MBOAT family. Only selected proteins are shown. Species and enzyme names are abbreviated: AT, Arabidopsis thaliana; BS, Bacillus subtilis; CE, Caenorhabditis elegans; DM, Drosophila melanogaster; HS, Homo sapiens; MM, Mus musculus; PA, Pseudomonas aeruginosa; SA, Staphylococcus aureus; SC, Saccharomyces cerevisiae; SI, Simmondsia chinensis; TP, Treponema pallidum; ACAT, cholesterol acyltransferase; DGAT, diacylglycerol O-acyltransferase; WaxSyn, wax synthase. Invariant residues and conservative substitutions in> 50% of the sequences are shown on black and gray background, respectively, and highly conserved polar residues are shown on a colored background. The numbers at the left of the alignment indicate the position in the sequence, the black bar on top indicates a long hydrophobic region.