Cytoskeletal differences between human neuroendocrine tumors: a cytoskeletal protein of molecular weight 46,000 distinguishes cutaneous from pulmonary …
R Moll, WW Franke - Differentiation, 1985 - Elsevier
The cytoskeletons of various human neuroendocrine (NE) tumors were analyzed
immunohistochemically using antibodies against intermediate-filament (IF) proteins as well
as by two-dimensional gel electrophoresis of proteins from microdissected tissue samples.
All of the tumors studied were found to contain cytokeratin filaments and are therefore
referred to as 'NE tumors of the epithelial type'. In addition, neurofilaments were found in
most cutaneous and some pulmonary NE tumors, as well as in medullary carcinomas of the …
immunohistochemically using antibodies against intermediate-filament (IF) proteins as well
as by two-dimensional gel electrophoresis of proteins from microdissected tissue samples.
All of the tumors studied were found to contain cytokeratin filaments and are therefore
referred to as 'NE tumors of the epithelial type'. In addition, neurofilaments were found in
most cutaneous and some pulmonary NE tumors, as well as in medullary carcinomas of the …