Enterohaemorrhagic Escherichia coli in human medicine
H Karch, PI Tarr, M Bielaszewska - International Journal of Medical …, 2005 - Elsevier
Enterohaemorrhagic Escherichia coli (EHEC) are the pathogenic subgroup of Shiga toxin
(Stx)-producing E. coli. EHEC can cause non-bloody and bloody diarrhoea, and the
haemolytic uraemic syndrome (HUS). HUS is a major cause of acute renal failure in
children. E. coli O157: H7 is the predominant, but far from being the only, serotype that can
cause HUS. The cascade leading from gastrointestinal infection to renal impairment is
complex, with the microvascular endothelium being the major histopathological target …
(Stx)-producing E. coli. EHEC can cause non-bloody and bloody diarrhoea, and the
haemolytic uraemic syndrome (HUS). HUS is a major cause of acute renal failure in
children. E. coli O157: H7 is the predominant, but far from being the only, serotype that can
cause HUS. The cascade leading from gastrointestinal infection to renal impairment is
complex, with the microvascular endothelium being the major histopathological target …