[HTML][HTML] Effect of Shiga toxin and Shiga-like toxins on eukaryotic cells
EV O'Loughlin, RM Robins-Browne - Microbes and infection, 2001 - Elsevier
Shigella dysenteriae and Shiga-toxin-producing Escherichia coli (STEC) elaborate the AB
holotoxins, Shiga or Shiga-like toxins (Stx). Stx play a major role in the pathogenesis of
haemorrhagic colitis and haemolytic uremic syndrome. This review provides an overview of
the mechanisms of action of Stx and a model of the pathogenesis of Stx-induced disease.
holotoxins, Shiga or Shiga-like toxins (Stx). Stx play a major role in the pathogenesis of
haemorrhagic colitis and haemolytic uremic syndrome. This review provides an overview of
the mechanisms of action of Stx and a model of the pathogenesis of Stx-induced disease.