Immunohistochemical localization of the neuron-specific glucose transporter (GLUT3) to neuropil in adult rat brain
AL McCall, AM Van Bueren, M Moholt-Siebert… - Brain research, 1994 - Elsevier
AL McCall, AM Van Bueren, M Moholt-Siebert, NJ Cherry, WR Woodward
Brain research, 1994•ElsevierThe precise histologic localization of GLUT3, a glucose transporter thought to be restricted to
neurons, is unknown. Using a high-affinity, specific antiserum against rodent GLUT3 for
immunocytochemistry, light microscopic staining concentrates heterogeneously in the
neuropil in a region-and lamina-specific manner; intense staining characterizes areas with
high rates of glucose utilization such as inferior colliculus and pyriform cortex. Neuropil
localization with little perikaryal staining suggests that GLUT3 may provide the energy …
neurons, is unknown. Using a high-affinity, specific antiserum against rodent GLUT3 for
immunocytochemistry, light microscopic staining concentrates heterogeneously in the
neuropil in a region-and lamina-specific manner; intense staining characterizes areas with
high rates of glucose utilization such as inferior colliculus and pyriform cortex. Neuropil
localization with little perikaryal staining suggests that GLUT3 may provide the energy …
Abstract
The precise histologic localization of GLUT3, a glucose transporter thought to be restricted to neurons, is unknown. Using a high-affinity, specific antiserum against rodent GLUT3 for immunocytochemistry, light microscopic staining concentrates heterogeneously in the neuropil in a region- and lamina-specific manner; intense staining characterizes areas with high rates of glucose utilization such as inferior colliculus and pyriform cortex. Neuropil localization with little perikaryal staining suggests that GLUT3 may provide the energy needed locally for synaptic transmission.
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