Serum vascular endothelial growth factor-D prospectively distinguishes lymphangioleiomyomatosis from other diseases
LR Young, R VanDyke, PM Gulleman, Y Inoue… - Chest, 2010 - Elsevier
Objectives The majority of women with lymphangioleiomyomatosis (LAM) present with cystic
lung disease, and most require lung biopsy for definitive diagnosis. The purpose of this
study was to determine the prospective diagnostic usefulness of a serologic test for vascular
endothelial growth factor-D (VEGF-D), a lymphangiogenic growth factor. Methods We
prospectively measured serum VEGF-D levels by enzyme-linked immunoassay in 48
women presenting with cystic lung disease. Diagnostic test performance was determined …
lung disease, and most require lung biopsy for definitive diagnosis. The purpose of this
study was to determine the prospective diagnostic usefulness of a serologic test for vascular
endothelial growth factor-D (VEGF-D), a lymphangiogenic growth factor. Methods We
prospectively measured serum VEGF-D levels by enzyme-linked immunoassay in 48
women presenting with cystic lung disease. Diagnostic test performance was determined …