[HTML][HTML] Reconstructive problems in canine liver homotransplantation with special reference to the postoperative role of hepatic venous flow

TE Starzl, HA Kaupp Jr, DR Brock… - Surgery, gynecology …, 1960 - ncbi.nlm.nih.gov
TE Starzl, HA Kaupp Jr, DR Brock, RE Lazarus, RV Johnson
Surgery, gynecology & obstetrics, 1960ncbi.nlm.nih.gov
Although considerable experimental data have accumulated concerning many organs, there
have been few reports of homotransplantation of the liver. Until 1959, the only work had
been done by Welch and his associates (9, 34), who were able to obtain function from liver
homografts transplanted into the pelvis. Recently, Moore and his associates presented the
first accounts of successful homotransplantation of the canine liver to animals with total
hepatectomy (21, 22). Maximum survival after operation was 12 days. The techniques to be …
Although considerable experimental data have accumulated concerning many organs, there have been few reports of homotransplantation of the liver. Until 1959, the only work had been done by Welch and his associates (9, 34), who were able to obtain function from liver homografts transplanted into the pelvis. Recently, Moore and his associates presented the first accounts of successful homotransplantation of the canine liver to animals with total hepatectomy (21, 22). Maximum survival after operation was 12 days.
The techniques to be described for homotransplantation of the liver have previously been briefly outlined (12, 28). The influence of portal flow upon the homografted liver has been analyzed in detail not only be-cause this factor proved to be an important determinant of success or failure but also because the resultant information may have application in a variety of other experimental situations, including those involving hemorrhagic shock. Maximum survival after liver homotransplantation has been 20½ days.
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