Long-term management of prolactinomas

JA Schlechte - The Journal of Clinical Endocrinology & …, 2007 - academic.oup.com
JA Schlechte
The Journal of Clinical Endocrinology & Metabolism, 2007academic.oup.com
Prolactinomas are a frequent cause of gonadal dysfunction and infertility, especially in
young women. The regulation of prolactin secretion and the efficacy of dopamine agonists in
the therapy of prolactinomas are well established. The current challenges in management of
prolactinomas are related to follow-up after successful therapy. Issues and questions to be
addressed in this approach to long-term management of prolactinomas include the
frequency of radiographic monitoring, effect of pregnancy and menopause, safety of …
Abstract
Prolactinomas are a frequent cause of gonadal dysfunction and infertility, especially in young women. The regulation of prolactin secretion and the efficacy of dopamine agonists in the therapy of prolactinomas are well established. The current challenges in management of prolactinomas are related to follow-up after successful therapy. Issues and questions to be addressed in this approach to long-term management of prolactinomas include the frequency of radiographic monitoring, effect of pregnancy and menopause, safety of estrogen in women taking oral contraceptives, and the potential for discontinuation of dopamine agonist therapy.
Oxford University Press