Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline

S Melmed, FF Casanueva, AR Hoffman… - The Journal of …, 2011 - academic.oup.com
S Melmed, FF Casanueva, AR Hoffman, DL Kleinberg, VM Montori, JA Schlechte, JAH Wass
The Journal of Clinical Endocrinology & Metabolism, 2011academic.oup.com
abstract Objective: The aim was to formulate practice guidelines for the diagnosis and
treatment of hyperprolactinemia. Participants: The Task Force consisted of Endocrine
Society-appointed experts, a methodologist, and a medical writer. Evidence: This evidence-
based guideline was developed using the Grading of Recommendations, Assessment,
Development, and Evaluation (GRADE) system to describe both the strength of
recommendations and the quality of evidence. Consensus Process: One group meeting …
Objective
The aim was to formulate practice guidelines for the diagnosis and treatment of hyperprolactinemia.
Participants
The Task Force consisted of Endocrine Society-appointed experts, a methodologist, and a medical writer.
Evidence
This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence.
Consensus Process
One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of The Endocrine Society, The European Society of Endocrinology, and The Pituitary Society reviewed and commented on preliminary drafts of these guidelines.
Conclusions
Practice guidelines are presented for diagnosis and treatment of patients with elevated prolactin levels. These include evidence-based approaches to assessing the cause of hyperprolactinemia, treating drug-induced hyperprolactinemia, and managing prolactinomas in nonpregnant and pregnant subjects. Indications and side effects of therapeutic agents for treating prolactinomas are also presented.
Oxford University Press