Endogenous and exogenous insulin responses in patients with cystic fibrosis

EG Wilmshurst, JS Soeldner, DS Holsclaw… - …, 1975 - publications.aap.org
Eight male patients with cystic fibrosis, normal nutrition, normal physical activity, relatively
mild pulmonary disease, no evidence of liver disease and no family history of diabetes
mellitus underwent a series of carbohydrate tolerance tests in comparison with a group of 18
normal male subjects matched for age and body weight. Compared with the normal group,
the patients with cystic fibrosis had significantly impaired glucose tolerance and significantly
lower serum immunoreactive insulin levels during oral and intravenous glucose tolerance …