[HTML][HTML] Central role of the P2Y12 receptor in platelet activation
RT Dorsam, SP Kunapuli - The Journal of clinical …, 2004 - Am Soc Clin Investig
RT Dorsam, SP Kunapuli
The Journal of clinical investigation, 2004•Am Soc Clin InvestigPlatelet activation occurs in response to vessel injury and is important for the arrest of
bleeding. Platelet activation during disease states leads to vascular occlusion and ischemic
damage. The P2Y12 receptor, activated by ADP, plays a central role in platelet activation
and is the target of P2Y12 receptor antagonists that have proven therapeutic value.
bleeding. Platelet activation during disease states leads to vascular occlusion and ischemic
damage. The P2Y12 receptor, activated by ADP, plays a central role in platelet activation
and is the target of P2Y12 receptor antagonists that have proven therapeutic value.
Platelet activation occurs in response to vessel injury and is important for the arrest of bleeding. Platelet activation during disease states leads to vascular occlusion and ischemic damage. The P2Y12 receptor, activated by ADP, plays a central role in platelet activation and is the target of P2Y12 receptor antagonists that have proven therapeutic value.
The Journal of Clinical Investigation