Friendly and dangerous signals: is the tissue in control?

P Matzinger - Nature immunology, 2007 - nature.com
P Matzinger
Nature immunology, 2007nature.com
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In their own defense, tissues send a panoply of signals that initiate immunity and guide the choice of effector class. TH1-TH2 and Treg is far too simple a representation of the breathtaking variety of the resulting responses.
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