[PDF][PDF] Serotonin receptors: Genetic insights into serotonin function

MJS Heath, R Hen - Current Biology, 1995 - cell.com
MJS Heath, R Hen
Current Biology, 1995cell.com
Genetic insights into serotonin function Page 1 MARK JS HEATH AND RENE HEN SEROTONIN
RECEPTORS Genetic insights into serotonin function Targeted disruption of the genes for the
5-HT 1B and 5-HT2c serotonin receptors and monoamine oxidase A have confirmed
pharmacological experiments and revealed unexpected behavioral roles for serotonin.
Serotonin (5-hydroxytryptamine, 5-HT) is a biogenic monoamine found in a wide variety of sites
in the central and peripheral nervous systems. Serotonergic signaling appears to play a key role …
Abstract
Targeted disruption of the genes for the 5-HT1B and 5-HT2C serotonin receptors and monoamine oxidase A have confirmed pharmacological experiments and revealed unexpected behavioral roles for serotonin.
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