[HTML][HTML] Clinical and biological significance of RAS mutations in multiple myeloma

WJ Chng, N Gonzalez-Paz, T Price-Troska, S Jacobus… - Leukemia, 2008 - nature.com
WJ Chng, N Gonzalez-Paz, T Price-Troska, S Jacobus, SV Rajkumar, MM Oken, RA Kyle…
Leukemia, 2008nature.com
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Hiwatari M, Taki T, Tsuchida M, Hanada R, Hongo T, Sako M et al. Novel missense …
2 Fletcher JA. Role of KIT and Platelet-Derived Growth Factor Receptors as Oncoproteins. Seminars in Oncology 2004; 31: 4–11. 3 Hirota S, Nishida T, Isozaki K, Taniguchi M, Nakamura J, Okazaki T et al. Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours. Journal of Pathology 2001; 193: 505–510. 4 Tefferi1 A, Gilliland DG. Oncogenes in Myeloproliferative Disorders. Cell Cycle 2007; 5: 550–566. 5 Hiwatari M, Taki T, Tsuchida M, Hanada R, Hongo T, Sako M et al. Novel missense mutations in the tyrosine kinase domain of the platelet-derived growth factor receptor alpha (PDGFRA) gene in childhood acute myeloid leukemia with t (8; 21)(q22; q22) or inv (16)(p13q22). Leukemia 2005; 19: 476–477. 6 Burgstaller S, Kreil S, Waghorn K, Metzgeroth G, Preudhomme C, Zoi K et al. The severity of FIP1L1–PDGFRA-positive chronic eosinophilic leukaemia is associated with polymorphic variation at the IL5RA locus. Leukemia 2007; 21: 2428–2432. 7 Wang YY, Zhou GB, Yin T, Chen B, Shi JY, Liang WX et al. AML1–ETO and C–KIT mutation/overexpression in t (8; 21) leukemia: Implication in stepwise leukemogenesis and response to Gleevec.
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