The Flp Recombinase of th 2-μm Plasmid of Saccharomyces cerevisiae

PD Sadowski - Progress in nucleic acid research and molecular …, 1995 - Elsevier
Publisher Summary Most strains of the yeast, Saccharomyces cerevisiae, harbor about 100
copies of an autonomously replicating plasmid, the 2-μm plasmid. Although the plasmid
confers no advantage to its host, it is very stable. Because of its high copy-number and
stability, the 2-μm plasmid has been a useful model for studying DNA replication,
recombination, regulation of gene expression, and plasmid segregation in eukaryotic
organisms. The plasmid has also served as the basis of many important autonomously …