Thyroid hormone (TR) and liver X (LXR) receptors are transcription factors involved in
lipogenesis. Both receptors recognize the same consensus DNA-response element in vitro.
It was previously shown that their signaling pathways interact in the control of cholesterol
elimination in the liver. In the present study, carbohydrate-response element-binding protein
(ChREBP), a major transcription factor controlling the activation of glucose-induced
lipogenesis in liver, is characterized as a direct target of thyroid hormones (TH) in liver and …