Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury

KD Liu, DV Glidden, MD Eisner, PE Parsons… - Critical care …, 2007 - journals.lww.com
Objective: To identify biological and clinical predictors of acute kidney injury in subjects with
acute lung injury. Design: Secondary data analysis from a multicenter, randomized clinical
trial. Setting: Intensive care units in ten university medical centers. Patients: A total of 876
patients enrolled in the first National Heart, Lung, and Blood Institute Acute Respiratory
Distress Syndrome Clinical Network trial. Interventions: Study subjects were randomized to
receive a low tidal volume ventilation strategy and pharmacologic therapy with ketoconazole …