Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial
RW Taylor, JL Zimmerman, RP Dellinger, RC Straube… - Jama, 2004 - jamanetwork.com
ContextInhaled nitric oxide has been shown to improve oxygenation in acute lung injury.
ObjectiveTo evaluate the clinical efficacy of low-dose (5-ppm) inhaled nitric oxide in patients
with acute lung injury. Design and SettingMulticenter, randomized, placebo-controlled study,
with blinding of patients, caregivers, data collectors, assessors of outcomes, and data
analysts (triple blind), conducted in the intensive care units of 46 hospitals in the United
States. Patients were enrolled between March 1996 and September 1999. PatientsPatients …
ObjectiveTo evaluate the clinical efficacy of low-dose (5-ppm) inhaled nitric oxide in patients
with acute lung injury. Design and SettingMulticenter, randomized, placebo-controlled study,
with blinding of patients, caregivers, data collectors, assessors of outcomes, and data
analysts (triple blind), conducted in the intensive care units of 46 hospitals in the United
States. Patients were enrolled between March 1996 and September 1999. PatientsPatients …