Alarmins and antimicrobial immunity

D Yang, JJ Oppenheim - Medical mycology, 2009 - academic.oup.com
D Yang, JJ Oppenheim
Medical mycology, 2009academic.oup.com
Alarmins are endogenous mediators capable of enhancing innate and adaptive immune
response through induction of concomitant recruitment and activation of antigen-presenting
cells. Here we provide a brief overview of various alarmins, highlight their critical roles in
innate and adaptive antimicrobial immunity, and speculate on potential usage of alarmins in
combating aspergillosis.
Abstract
Alarmins are endogenous mediators capable of enhancing innate and adaptive immune response through induction of concomitant recruitment and activation of antigen-presenting cells. Here we provide a brief overview of various alarmins, highlight their critical roles in innate and adaptive antimicrobial immunity, and speculate on potential usage of alarmins in combating aspergillosis.
Oxford University Press