Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study
GA Block, TE Hulbert-Shearon, NW Levin… - American Journal of …, 1998 - ajkd.org
Elevated serum phosphorus is a predictable accompaniment of end-stage renal disease
(ESRD) in the absence of dietary phosphate restriction or supplemental phosphate binders.
The consequences of hyperphosphatemia include the development and progression of
secondary hyperparathyroidism and a predisposition to metastatic calcification when the
product of serum calcium and phosphorus (Ca x PO4) is elevated. Both of these conditions
may contribute to the substantial morbidity and mortality seen in patients with ESRD. We …
(ESRD) in the absence of dietary phosphate restriction or supplemental phosphate binders.
The consequences of hyperphosphatemia include the development and progression of
secondary hyperparathyroidism and a predisposition to metastatic calcification when the
product of serum calcium and phosphorus (Ca x PO4) is elevated. Both of these conditions
may contribute to the substantial morbidity and mortality seen in patients with ESRD. We …