The molecular mechanics of eukaryotic translation
LD Kapp, JR Lorsch - Annual review of biochemistry, 2004 - annualreviews.org
LD Kapp, JR Lorsch
Annual review of biochemistry, 2004•annualreviews.org▪ Abstract Great advances have been made in the past three decades in understanding the
molecular mechanics underlying protein synthesis in bacteria, but our understanding of the
corresponding events in eukaryotic organisms is only beginning to catch up. In this review
we describe the current state of our knowledge and ignorance of the molecular mechanics
underlying eukaryotic translation. We discuss the mechanisms conserved across the three
kingdoms of life as well as the important divergences that have taken place in the pathway.
molecular mechanics underlying protein synthesis in bacteria, but our understanding of the
corresponding events in eukaryotic organisms is only beginning to catch up. In this review
we describe the current state of our knowledge and ignorance of the molecular mechanics
underlying eukaryotic translation. We discuss the mechanisms conserved across the three
kingdoms of life as well as the important divergences that have taken place in the pathway.
▪ Abstract
Great advances have been made in the past three decades in understanding the molecular mechanics underlying protein synthesis in bacteria, but our understanding of the corresponding events in eukaryotic organisms is only beginning to catch up. In this review we describe the current state of our knowledge and ignorance of the molecular mechanics underlying eukaryotic translation. We discuss the mechanisms conserved across the three kingdoms of life as well as the important divergences that have taken place in the pathway.
Annual Reviews