Increased endothelial cell turnover in areas of in vivo Evans Blue uptake in the pig aorta

BA Caplan, CJ Schwartz - Atherosclerosis, 1973 - Elsevier
Focal areas of spontaneous increased aortic endothelial permeability to the protein-binding
azo dye Evans Blue in vivo have been further characterized in 8–12 week-old
normocholesterolaemic pigs by means of Häutchen preparations with [3 H] thymidine
autoradiography, together with observations on endothelial cell length, cell area, and
surface morphology. Endothelial cell turnover was significantly greater in areas of dye
accumulation than in contiguous areas showing no dye accumulation. No differences in …