Serum creatine-kinase (CK) and pyruvate-kinase (PK) activities in Duchenne (DMD) as compared with Becker (BMD) muscular dystrophy

M Zatz, D Rapaport, M Vainzof… - Journal of the …, 1991 - Elsevier
Serum creatine-kinase (CK) activities were determined in 536 patients affected with X-linked
muscular dystrophy (456 with Duchenne or DMD and 80 with Becker or BMD) and serum
pyruvate-kinase (PK) in 360 among them (309 DMD and 51 BMD). The aim of this
investigation was to assess the variability and rate of decrease in serum activity in DMD as
compared with BMD as a function of age and in DMD as a function of Vignos scale as well.
In DMD, maximum CK and PK activities were found around 1–6 years old and the average …