Sirt1: a metabolic master switch that modulates lifespan
IB Leibiger, PO Berggren - Nature medicine, 2006 - nature.com
IB Leibiger, PO Berggren
Nature medicine, 2006•nature.comSirt1: a metabolic master switch that modulates lifespan | Nature Medicine Skip to main content
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Sirt1, an enzyme that removes acetyl groups from specific nuclear proteins, has been linked to the regulation of aging. It is now clear that Sirt1 also controls hepatic glucose metabolism by serving as a sensor of the metabolic status in hepatocytes.
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