[PDF][PDF] High-risk human papillomavirus affects prognosis in patients with surgically treated oropharyngeal squamous cell carcinoma
L Licitra, F Perrone, P Bossi, S Suardi… - Journal of Clinical …, 2006 - academia.edu
Journal of Clinical Oncology, 2006•academia.edu
Purpose Human papillomavirus (HPV) DNA tumors actively integrating the E6 and E7
oncogenes have a distinct biologic behavior resulting in a more favorable prognosis. To
which extent the viral integration by itself, and/or the associated wild-type (wt) TP53 status,
and/or a functional p16 contribute to prognosis is unclear.
oncogenes have a distinct biologic behavior resulting in a more favorable prognosis. To
which extent the viral integration by itself, and/or the associated wild-type (wt) TP53 status,
and/or a functional p16 contribute to prognosis is unclear.
Purpose
Human papillomavirus (HPV) DNA tumors actively integrating the E6 and E7 oncogenes have a distinct biologic behavior resulting in a more favorable prognosis. To which extent the viral integration by itself, and/or the associated wild-type (wt) TP53 status, and/or a functional p16 contribute to prognosis is unclear.
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