Cellular and molecular pathways linking inflammation and cancer

C Porta, P Larghi, M Rimoldi, MG Totaro, P Allavena… - Immunobiology, 2009 - Elsevier
Several experimental and epidemiological evidence indicate that, irrespective of the trigger
for the development (chronic infection/inflammation or genetic alteration), a “smouldering”
inflammation is associated with the most of, if not all, tumours and supports their
progression. Several evidence have highlighted that tumours promote a constant influx of
myelomonocytic cells that express inflammatory mediators supporting pro-tumoral functions.
Myelomonocytic cells are key orchestrators of cancer-related inflammation associated with …