Treatment of acute renal failure secondary to multiple myeloma with chemotherapy and extended high cut-off hemodialysis

CA Hutchison, AR Bradwell, M Cook… - Clinical Journal of the …, 2009 - journals.lww.com
Background and objectives: Extended hemodialysis using a high cut-off dialyzer (HCO-HD)
removes large quantities of free light chains in patients with multiple myeloma. However, the
clinical utility of this method is uncertain. This study assessed the combination of
chemotherapy and HCO-HD on serum free light chain concentrations and renal recovery in
patients with myeloma kidney (cast nephropathy) and dialysis-dependent acute renal failure.