Studies of polymorphonuclear leukocytes from patients with chronic granulomatous disease of childhood: bactericidal capacity for streptococci

EL Kaplan, T Laxdal, PG Quie - Pediatrics, 1968 - publications.aap.org
Polymorphonuclear leukocytes (PMNs) from children with chronic granulomatous disease of
childhood have been shown to readily phagocytize staphylococci and certain gram-negative
bacteria, but they demonstrate an impaired intracellular bactericidal capacity for these
organisms. The in vitro phagocytic and bactericidal capacities of PMNs from three patients
with this disease for four species of streptococci (Streptococcus faecalis, Streptococcus
viridans, microaerophlic streptococci, and Streptococcus pyogenes) were tested by the …