[PDF][PDF] Massive blood transfusion
MDJ Donaldson, MJ Seaman, GR Park - British Journal of Anaesthesia, 1992 - emcrit.org
MDJ Donaldson, MJ Seaman, GR Park
British Journal of Anaesthesia, 1992•emcrit.orgMassive blood transfusion may be defined either as the acute administration of more than
1.5 times the patient's estimated blood volume [36], or as the replacement of the patient's
total blood volume by stored homologous bank blood in less than 24 h [18]. The purpose of
this review is to provide the reader with a practical approach to the initial management of the
acutely bleeding, hypovolaemic patient, together with a description of some of the newer
agents and techniques now available to treat major haemorrhage. Acute haemorrhage …
1.5 times the patient's estimated blood volume [36], or as the replacement of the patient's
total blood volume by stored homologous bank blood in less than 24 h [18]. The purpose of
this review is to provide the reader with a practical approach to the initial management of the
acutely bleeding, hypovolaemic patient, together with a description of some of the newer
agents and techniques now available to treat major haemorrhage. Acute haemorrhage …
Massive blood transfusion may be defined either as the acute administration of more than 1.5 times the patient's estimated blood volume [36], or as the replacement of the patient's total blood volume by stored homologous bank blood in less than 24 h [18]. The purpose of this review is to provide the reader with a practical approach to the initial management of the acutely bleeding, hypovolaemic patient, together with a description of some of the newer agents and techniques now available to treat major haemorrhage.
Acute haemorrhage leading to acute hypovolaemic shock is a medical emergency carrying a high mortality and therefore requires prompt and effective treatment. Initial management includes rapid restoration of the circulating blood volume, correction and maintenance of adequate haemostasis, oxygen delivery and colloid osmotic pressure and correction of any biochemical abnormalities. The investigation and treatment of the underlying cause of bleeding should also be undertaken as soon as possible (table I).
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