Naturally occurring primary deficiencies of the immune system
A Fischer, M Cavazzana-Calvo… - Annual review of …, 1997 - annualreviews.org
A Fischer, M Cavazzana-Calvo, GDS Basile, JP DeVillartay, JP Di Santo, C Hivroz…
Annual review of immunology, 1997•annualreviews.org▪ Abstract Naturally occurring genetic disorders of the immune system provide many models
for the study of its development and function. In a way, their analysis complements the
information provided by the generation of genetic defects in mice created using homologous
recombination techniques. In this review, the recent findings made in three areas are
focused upon deficiencies in T cell differentiation and in T lymphocyte activation, and on the
control process of peripheral immune response.
for the study of its development and function. In a way, their analysis complements the
information provided by the generation of genetic defects in mice created using homologous
recombination techniques. In this review, the recent findings made in three areas are
focused upon deficiencies in T cell differentiation and in T lymphocyte activation, and on the
control process of peripheral immune response.
▪ Abstract
Naturally occurring genetic disorders of the immune system provide many models for the study of its development and function. In a way, their analysis complements the information provided by the generation of genetic defects in mice created using homologous recombination techniques. In this review, the recent findings made in three areas are focused upon deficiencies in T cell differentiation and in T lymphocyte activation, and on the control process of peripheral immune response.
Annual Reviews