Dendritic cells (DCs) are a heterogeneous population of migratory cells specialized for the
uptake, processing, and presentation of antigen to T cells. They consist of a variety of mature
subpopulations, classically divided into “lymphoid” and “myeloid” subsets. Although there
likely exists significant plasticity and redundancy between DC subpopulations, unique
differences have been noted in their abilities for T cell stimulation, tolerance induction, T
helper cell polarization, cytokine secretion, and anatomic localization. Although DCs are …