[CITATION][C] [13] Murine experimental autoimmune encephalomyelitis: A model of immune-mediated inflammation and multiple sclerosis
AR Glabinski, M Tani, VK Tuohy, RM Ransohoff - Methods in enzymology, 1997 - Elsevier
The classic description of multiple sclerosis (MS) pathology by Charcot placed major
emphasis on the fact that myelin was destroyed in central nervous system (CNS) tissues of
affected individuals, whereas axons were relatively sparedJ Multiple sclerosis was thus
categorized as a disease of primary demyelination. The history of research into MS has
marched hand in hand with research of animal models of demyelination, which are grouped
in three major categories, according to etiology, as immune-mediated, virusinduced, and …
emphasis on the fact that myelin was destroyed in central nervous system (CNS) tissues of
affected individuals, whereas axons were relatively sparedJ Multiple sclerosis was thus
categorized as a disease of primary demyelination. The history of research into MS has
marched hand in hand with research of animal models of demyelination, which are grouped
in three major categories, according to etiology, as immune-mediated, virusinduced, and …