[PDF][PDF] MHC class I: an unexpected role in neuronal plasticity

CJ Shatz - Neuron, 2009 - cell.com
Neuron, 2009cell.com
For the nervous system to translate experience into memory and behavior, lasting structural
change at synapses must occur. This requirement is clearly evident during critical periods of
activity-dependent neural development, and accumulating evidence has established a
surprising role for the major histocompatibility complex class I (MHCI) proteins in this
process.
For the nervous system to translate experience into memory and behavior, lasting structural change at synapses must occur. This requirement is clearly evident during critical periods of activity-dependent neural development, and accumulating evidence has established a surprising role for the major histocompatibility complex class I (MHCI) proteins in this process.
cell.com