Enhanced thermogenic responsiveness during chronic ephedrine treatment in man

A Astrup, C Lundsgaard, J Madsen… - The American journal of …, 1985 - Elsevier
The thermogenic effect of a single oral dose of ephedrine (1 mg/kg body weight) was studied
by indirect calorimetry in five women with 14% overweight before, during and 2 mo after 3
mo of chronic ephedrine treatment (20 mg, perorally, three times daily). Before treatment and
2 mo after its cessation a similar thermogenic response to ephedrine was observed. The
total extra consumption of oxygen was 1.3 1 before and 1.2 1 after cessation of the chronic
treatment After 4 and 12 wk of treatment ephedrine elicited a more sustained response, the …