Voriconazole exposure and geographic location are independent risk factors for squamous cell carcinoma of the skin among lung transplant recipients
A Vadnerkar, MH Nguyen, D Mitsani, M Crespo… - The Journal of heart and …, 2010 - Elsevier
BACKGROUND: Skin cancer, in particular squamous cell carcinoma (SCC), is the most
common malignancy after solid-organ transplantation. SCC has been reported in
immunosuppressed patients receiving voriconazole, but the agent has not been shown to be
a risk factor. Universal voriconazole prophylaxis and alemtuzumab induction are standard in
our lung transplant program. METHODS: We performed a retrospective, case–control study
(matched 1: 3) among lung transplant recipients at our center from 2003 to 2008. RESULTS …
common malignancy after solid-organ transplantation. SCC has been reported in
immunosuppressed patients receiving voriconazole, but the agent has not been shown to be
a risk factor. Universal voriconazole prophylaxis and alemtuzumab induction are standard in
our lung transplant program. METHODS: We performed a retrospective, case–control study
(matched 1: 3) among lung transplant recipients at our center from 2003 to 2008. RESULTS …