MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
AJ Schetter, SY Leung, JJ Sohn, KA Zanetti… - Jama, 2008 - jamanetwork.com
ContextMicroRNAs have potential as diagnostic biomarkers and therapeutic targets in
cancer. No study has evaluated the association between microRNA expression patterns and
colon cancer prognosis or therapeutic outcome. ObjectiveTo identify microRNA expression
patterns associated with colon adenocarcinomas, prognosis, or therapeutic outcome.
Design, Setting, and Patients MicroRNA microarray expression profiling of tumors and
paired nontumorous tissues was performed on a US test cohort of 84 patients with incident …
cancer. No study has evaluated the association between microRNA expression patterns and
colon cancer prognosis or therapeutic outcome. ObjectiveTo identify microRNA expression
patterns associated with colon adenocarcinomas, prognosis, or therapeutic outcome.
Design, Setting, and Patients MicroRNA microarray expression profiling of tumors and
paired nontumorous tissues was performed on a US test cohort of 84 patients with incident …