Determination of the cholesterol–collagen ratio of arterial atherosclerotic plaques using near infrared spectroscopy as a possible measure of plaque stability

V Neumeister, M Scheibe, P Lattke, W Jaross - Atherosclerosis, 2002 - Elsevier
Particular danger associated with an arteriosclerotic plaque consists in the possible rupture
of its cap, dependent on the thickness of the cap covering the lipid core, its composition and
different inflammatory changes. The purpose of this study was to compare the total
cholesterol and collagen contents of arterial walls, both measured by near infrared
spectroscopy (NIRS), and to test whether the ratios of cholesterol to collagen correlate with
histochemical parameters possibly being indicators for plaque stability. NIR spectra of 118 …