DNA repair in neurons: so if they don't divide what's to repair?

ML Fishel, MR Vasko, MR Kelley - Mutation Research/Fundamental and …, 2007 - Elsevier
Neuronal DNA repair remains one of the most exciting areas for investigation, particularly as
a means to compare the DNA repair response in mitotic (cancer) vs. post-mitotic (neuronal)
cells. In addition, the role of DNA repair in neuronal cell survival and response to aging and
environmental insults is of particular interest. DNA damage caused by reactive oxygen
species (ROS) such as generated by mitochondrial respiration includes altered bases,
abasic sites, and single-and double-strand breaks which can be prevented by the DNA base …