Patients with chronic hepatitis C achieving a sustained virological response to peginterferon and ribavirin therapy recover from impaired hepcidin secretion
N Fujita, R Sugimoto, S Motonishi, N Tomosugi… - Journal of …, 2008 - Elsevier
BACKGROUND/AIMS: The aim of this study is to determine the clinical relevance of hepatic
producing iron regulatory hormone-hepcidin, on iron overload in patients with chronic
hepatitis C (CHC). METHODS: Serum hepcidin was measured in 73 CHC patients by
surface-enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF-
MS), and compared to those of healthy controls and anemia of inflammation patients, and
analyzed their relationship to hepatic hepcidin mRNA expression levels and clinical …
producing iron regulatory hormone-hepcidin, on iron overload in patients with chronic
hepatitis C (CHC). METHODS: Serum hepcidin was measured in 73 CHC patients by
surface-enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF-
MS), and compared to those of healthy controls and anemia of inflammation patients, and
analyzed their relationship to hepatic hepcidin mRNA expression levels and clinical …