[HTML][HTML] Parathyroid hormone-related protein regulates tumor-relevant genes in breast cancer cells
A Dittmer, M Vetter, D Schunke, PN Span… - Journal of Biological …, 2006 - ASBMB
The effect of endogenous parathyroid hormone-related protein (PTHrP) on gene expression
in breast cancer cells was studied. We suppressed PTHrP expression in MDA-MB-231 cells
by RNA interference and analyzed changes in gene expression by microarray analysis.
More than 200 genes showed altered expression in response to a PTHrP-specific small
interfering (si) RNA (siPTHrP). Cell cycle-regulating gene CDC2 and genes (CDC25B and
Tome-1) that control CDC2 activity showed increased expression in the presence of …
in breast cancer cells was studied. We suppressed PTHrP expression in MDA-MB-231 cells
by RNA interference and analyzed changes in gene expression by microarray analysis.
More than 200 genes showed altered expression in response to a PTHrP-specific small
interfering (si) RNA (siPTHrP). Cell cycle-regulating gene CDC2 and genes (CDC25B and
Tome-1) that control CDC2 activity showed increased expression in the presence of …