Clinical manifestations and management of neurofibromatosis type 1

JH Tonsgard - Seminars in pediatric neurology, 2006 - Elsevier
Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with variable expression.
The complications are age specific. Neurologic complications include tumors of the
peripheral nerves, nerve roots, and plexi; spinal cord compression; dural ectasias; learning
disabilities; attention deficit; headaches; seizures; brain tumors; deafness; hydrocephalus;
and stroke. High-intensity signals on brain magnetic resonance imaging are a frequent
finding without known clinical significance. Most brain tumors are benign and asymptomatic …