Genital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection

E Tronstein, C Johnston, ML Huang, S Selke… - Jama, 2011 - jamanetwork.com
Context Since herpes simplex virus type 2 (HSV-2) antibody tests have become
commercially available, an increasing number of persons have learned that they have
genital herpes through serologic testing. The course of natural history of HSV-2 in
asymptomatic, seropositive persons is uncertain. Objective To evaluate the virologic and
clinical course of HSV genital shedding among individuals with symptomatic and
asymptomatic HSV-2 infection. Design, Setting, and Participants Cohort of 498 …