[PDF][PDF] The Effects of Treponema pallidum on Human Dendritic Cells
JL Shin, KY Chung, JM Kang, TH Lee… - Yonsei medical …, 2004 - synapse.koreamed.org
Cell mediated immune responses play a prominent role in syphilis, which is caused by
Treponema pallidum. The role of dendritic cells (DC) in the syphilitic infection is not well
understood in human. In the present study, we studied interaction of T. pallidum with DC,
generated from human peripheral blood mononuclear cells with GM-CSF and IL-4. After
adding T. pallidum for 16 hours to immature DC at culture day 7, the change of surface
antigens on DC was monitored by flow cytometry, the amount of IL-12 in culture supernatant …
Treponema pallidum. The role of dendritic cells (DC) in the syphilitic infection is not well
understood in human. In the present study, we studied interaction of T. pallidum with DC,
generated from human peripheral blood mononuclear cells with GM-CSF and IL-4. After
adding T. pallidum for 16 hours to immature DC at culture day 7, the change of surface
antigens on DC was monitored by flow cytometry, the amount of IL-12 in culture supernatant …