Factors Associated with Absence of H2O2-Producing Lactobacillus among Women with Bacterial Vaginosis
RH Beigi, HC Wiesenfeld, SL Hillier… - The Journal of …, 2005 - academic.oup.com
RH Beigi, HC Wiesenfeld, SL Hillier, T Straw, MA Krohn
The Journal of infectious diseases, 2005•academic.oup.comBackground Women with bacterial vaginosis have different microbiological profiles. Our
objective was to identify risk factors for an absence of H2O2-producing lactobacilli among
women with bacterial vaginosis Methods We performed a retrospective analysis of 947
women with bacterial vaginosis who were enrolled in prospective studies investigating
vaginal colonization and genital-tract infections Results Women were categorized into 2
groups: those with H2O2-producing lactobacilli present (n= 191; 20.2%) and those with …
objective was to identify risk factors for an absence of H2O2-producing lactobacilli among
women with bacterial vaginosis Methods We performed a retrospective analysis of 947
women with bacterial vaginosis who were enrolled in prospective studies investigating
vaginal colonization and genital-tract infections Results Women were categorized into 2
groups: those with H2O2-producing lactobacilli present (n= 191; 20.2%) and those with …
Abstract
BackgroundWomen with bacterial vaginosis have different microbiological profiles. Our objective was to identify risk factors for an absence of H2O2-producing lactobacilli among women with bacterial vaginosis
MethodsWe performed a retrospective analysis of 947 women with bacterial vaginosis who were enrolled in prospective studies investigating vaginal colonization and genital-tract infections
ResultsWomen were categorized into 2 groups: those with H2O2-producing lactobacilli present (n=191; 20.2%) and those with H2O2-producing lactobacilli absent (n=756; 79.8%). Multivariate logistic regression demonstrated that douching ⩾2 times during the past month (odds ratio [OR], 2.5; 95% confidence interval [CI], 1.1–6.0) and having ⩾3 sex partners during the past year (OR, 4.5; 95% CI, 1.8–11.7) were predictive of an absence of H2O2-producing lactobacilli
ConclusionAmong women with bacterial vaginosis, H2O2-producing lactobacillus colonization is influenced by sexual activity and douching habits. These findings may have important implications for response to treatment, relapse rate, and risk for sexually-transmitted-disease acquisition among women with bacterial vaginosis
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