[HTML][HTML] Effect of anti‐platelet factor‐4/heparin antibody induction on early saphenous vein graft occlusion after coronary artery bypass surgery
TJ Gluckman, JB Segal, SP Schulman… - Journal of Thrombosis …, 2009 - Elsevier
Background: Antibodies to complexes of heparin and platelet factor 4 (PF4) are capable of
causing heparin‐induced thrombocytopenia (HIT). Recent evidence suggests that anti‐
PF4/heparin antibodies may be prothrombogenic even in the absence of thrombocytopenia
and clinically‐recognized HIT. Objectives: To determine if induction of anti‐PF4/heparin
antibodies is an independent risk factor for early saphenous vein graft (SVG) occlusion or
adverse clinical outcome after coronary artery bypass graft (CABG) surgery …
causing heparin‐induced thrombocytopenia (HIT). Recent evidence suggests that anti‐
PF4/heparin antibodies may be prothrombogenic even in the absence of thrombocytopenia
and clinically‐recognized HIT. Objectives: To determine if induction of anti‐PF4/heparin
antibodies is an independent risk factor for early saphenous vein graft (SVG) occlusion or
adverse clinical outcome after coronary artery bypass graft (CABG) surgery …