[HTML][HTML] A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases
PD Burbelo, D Drechsel, A Hall - Journal of Biological Chemistry, 1995 - ASBMB
Rho, Rac, and Cdc42 are small GTPases that regulate the formation of a variety of actin
structures and the assembly of associated integrin complexes, but little is known about the
target proteins that mediate their effects. Here we have used a motif-based search method to
identify putative effector proteins for Rac and Cdc42. A search of the GenBank™ data base
for similarity with the minimum Cdc42/Rac interactive binding (CRIB) region of a potential
effector protein p65 PAK has identified over 25 proteins containing a similar motif from a …
structures and the assembly of associated integrin complexes, but little is known about the
target proteins that mediate their effects. Here we have used a motif-based search method to
identify putative effector proteins for Rac and Cdc42. A search of the GenBank™ data base
for similarity with the minimum Cdc42/Rac interactive binding (CRIB) region of a potential
effector protein p65 PAK has identified over 25 proteins containing a similar motif from a …