The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited …
F De Winter, T Vo, FJ Stam, LAB Wisman… - Molecular and Cellular …, 2006 - Elsevier
Neuromuscular synapses differ markedly in their plasticity. Motor nerve terminals innervating
slow muscle fibers sprout vigorously following synaptic blockage, while those innervating
fast-fatigable muscle fibers fail to exhibit any sprouting. Here, we show that the axon
repellent Semaphorin 3A is differentially expressed in terminal Schwann cells (TSCs) on
different populations of muscle fibers: postnatal, regenerative and paralysis induced
remodeling of neuromuscular connections is accompanied by increased expression of …
slow muscle fibers sprout vigorously following synaptic blockage, while those innervating
fast-fatigable muscle fibers fail to exhibit any sprouting. Here, we show that the axon
repellent Semaphorin 3A is differentially expressed in terminal Schwann cells (TSCs) on
different populations of muscle fibers: postnatal, regenerative and paralysis induced
remodeling of neuromuscular connections is accompanied by increased expression of …