Immunohistochemistry of the liver and biliary tree in extrahepatic biliary atresia

M Davenport, C Gonde, R Redkar, G Koukoulis… - Journal of pediatric …, 2001 - Elsevier
Background: Progressive destruction of intrahepatic bile ducts may determine outcome in
extrahepatic biliary atresia (EHBA) despite successful portoenterostomy. The aim of this
study was to characterize the inflammatory infiltrate of a large series of cases of biliary
atresia and relate these findings to clinical outcome. Methods: Immunohistochemical
analysis was performed on frozen tissue sections of extrahepatic biliary tree and liver
biopsies obtained (August 1996 to March 1998) from 28 infants with EHBA and 8 liver …