Different expression of HLA-DR and ICAM-1 in livers from patients with biliary atresia and Byler's disease

U Broomé, A Nemeth, R Hultcrantz, A Scheynius - Journal of hepatology, 1997 - Elsevier
Background/Aims: Extrahepatic biliary atresia (EHBA) and chronic progressive intra-hepatic
cholestasis (Byler's disease) are two distinct disorders of unknown etiology in the neonate,
characterized by profound cholestasis. The aim of the present study was to investigate the
inflammatory reaction in liver tissue from patients with EHBA and Byler's disease. Methods:
The expression of HLA-DR and ICAM-1 and the number of CD4+, CD8+ and γ/δ+ T-cells
were investigated with immunoperoxidase technique on cryostat sections of liver tissue from …