Innate immunity to intracellular pathogens: macrophage receptors and responses to microbial entry
A Plüddemann, S Mukhopadhyay… - Immunological …, 2011 - Wiley Online Library
A Plüddemann, S Mukhopadhyay, S Gordon
Immunological reviews, 2011•Wiley Online LibraryInnate immunity to intracellular pathogens encompasses a range of interactions of cellular
and humoral activities of the host with the invading microorganism, determining the outcome
of infection. Here, we review the particular role of macrophage recognition receptors and
effector responses in the uptake of microbes and their products. We place this in context and
raise issues for discussion and further experimentation.
and humoral activities of the host with the invading microorganism, determining the outcome
of infection. Here, we review the particular role of macrophage recognition receptors and
effector responses in the uptake of microbes and their products. We place this in context and
raise issues for discussion and further experimentation.
Summary
Innate immunity to intracellular pathogens encompasses a range of interactions of cellular and humoral activities of the host with the invading microorganism, determining the outcome of infection. Here, we review the particular role of macrophage recognition receptors and effector responses in the uptake of microbes and their products. We place this in context and raise issues for discussion and further experimentation.
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